Method of DNA sequencing by polymerisation
US9738928B2 · kind B2 · utility
0Cited by
5References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 26, 2016 |
| Grant date | Aug 22, 2017 |
| Priority date | — |
| Expiry date | Oct 26, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6874
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the determination of a nucleic acid sequence by physical manipulation. The method is based on the precise determination of the localization of the replicating fork on the template by measuring the physical distance between one end of the molecule and the fork. This allows the determination of the physical location of the site where a pause or a blockage of the replication occurs, and deducing therefrom information on the sequence of the nucleic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.