Nucleic acid sequence analysis
US9738929B2 · kind B2 · utility
63Cited by
47References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2016 |
| Grant date | Aug 22, 2017 |
| Priority date | — |
| Expiry date | Dec 19, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.