Patent · US Active

Evaluation of co-registered images of differently stained tissue slices

US9740912B2 · kind B2 · utility

2Cited by

2References

17Claims

0Family size

Assignee

Definiens GmbH · DE

Inventors

Ralf Schoenmeyer · Gilching, DE
Gerd Binnig · Richterswil, CH
Guenter Schmidt · Leun, DE
Maria Athelogou · Munich, DE
Peter Ellenberg · Munich, DE

Key dates

Filing date	Dec 20, 2011
Grant date	Aug 22, 2017
Priority date	—
Expiry date	Dec 1, 2035

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30024
WIPO fieldComputer technology
WIPO sectorElectrical engineering

Abstract

A method for co-registering images of tissue slices stained with different biomarkers displays a first digital image of a first tissue slice on a graphical user interface such that an area of the first image is enclosed by a frame. Then a portion of a second image of a second tissue slice is displayed such that the area of the first image enclosed by the frame is co-registered with the displayed portion of the second image. The displayed portion of the second image has the shape of the frame. The tissue slices are both z slices of a tissue sample taken at corresponding positions in the x and y dimensions. The displayed portion of the second image is shifted in the x and y dimensions to coincide with the area of the first image that is enclosed by the frame as the user shifts the first image under the frame.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.