Photoacoustic catheter for functional-imaging-based ablation monitoring
US9743881B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2012 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Dec 26, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2576/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Functional imaging for localization in biological tissue entails measuring a response in the tissue (240) to electromagnetic radiation. A catheter (200) for real-time monitoring of cardiac ablation is employed to distinguish a hemorrhage zone (232) from the sandwiching necrotic and healthy tissue, or to distinguish exogenous photoacoustic contrast agent from bordering native tissue. A pair of wavelengths is selected for differential absorption (244) of the radiation in, correspondingly, the hemorrhage zone or where the contrast agent exists, and relatively similar absorption elsewhere. Near infrared laser or LED light may be used photoacoustically to serially acquire (S310, S320) the two datasets to be compared, each representative of a time waveform. Alternatively, acquisition is for a pair of wavelength bands of microwave-induced thermoacoustic data. In either case, the members of the dataset pair are combined (110, 122) by subtraction or division to effect the piece-wise cancellation/enhancement for display (218) of the resulting signal in real time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.