Macromolecules
US9744246B2 · kind B2 · utility
3Cited by
4References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2012 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Jun 6, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G83/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a macromolecule comprising a dendrimer having surface amino groups to which at least two different terminal groups are attached including a pharmaceutically active agent and a pharmacokinetic modifying agent, the pharmaceutically active agent comprising a hydroxyl group and being attached to the surface amino group of the dendrimer through a diacid linker. Pharmaceutical compositions comprising the macromolecules and methods of treatment using the macromolecules are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.