Compounds and methods for treating cancer by inhibiting the urokinase receptor
US9745288B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Aug 16, 2012 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Apr 5, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds and methods for treating or preventing cancer associated with binding to the urokinase receptor are provided. Biological processes affected by the compounds include cell migration, cell growth, cell adhesion, angiogenesis, cancer cell invasion, apoptosis, tumor formation, tumor progression, metastasis, degradation of the extracellular matrix, pericellular proteolysis, activation of plasminogen, changes in the levels of an extracellular protease, and changes in the levels of a VEGF receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.