Patent · US Active

Partially cross-linked esterified cellulose ethers

US9745387B2 · kind B2 · utility

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4References
15Claims
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Key dates

Filing dateAug 15, 2013
Grant dateAug 29, 2017
Priority date
Expiry dateNov 30, 2033

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/146
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A partially cross-linked esterified cellulose ether having A) groups of the formula —C(O)—R—COOA or a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>100 k)−Wf(>100 k)XL]/Wf(>100 k)XL is at least 0.20, wherein Wf(>100 k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>100 k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.