Method of improving cell proliferation of pancreatic progenitor cells in a pancreatic cell culture
US9745554B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jan 18, 2007 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Nov 22, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the discovery that the proliferation and survival of pancreatic progenitor cells can be enhanced by contacting the cells with, (1) a caspase inhibitor sufficient to reduce apoptosis in the pancreatic endocrine cells; and, (2) a growth factor in an amount sufficient to increase the level of activated Akt in the pancreatic endocrine cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.