RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
US9745574B2 · kind B2 · utility
40Cited by
243References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 4, 2010 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Feb 4, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/51
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded region connected to a single stranded region of phosphorothioate modified nucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.