Processes and recombinant microorganisms for the production of cadaverine
US9745608B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2012 |
| Grant date | Aug 29, 2017 |
| Priority date | — |
| Expiry date | Dec 27, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine or N-acetylcadaverine, as well as recombinant DNA molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced N-acetylcadaverine forming activity. Processes for the production of cadaverine N-acetylcadaverine using the recombinant microorganisms are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.