Patent · US Active

Heteroaryls and uses thereof

US9751854B2 · kind B2 · utility

2Cited by

1References

8Claims

0Family size

Assignee

Millennium Pharmaceuticals, Inc. · US

Inventors

Indu T. Bharathan · Somerville, US
Chris Blackburn · Natick, US
Jeffrey P. Ciavarri · Reading, US
Jouhara Chouitar · Stoughton, US
Courtney A. Cullis · Bedford, US
Natalie D'Amore · Lynnfield, US
Paul E. Fleming · Wellesley, US
Kenneth M. Gigstad · Westford, US
Krista E. Gipson · Medford, US
Mario Girard · Quincy, US
Yongbo Hu · Winchester, US
Janice Lee · Cambridge, US
Gang Li · Beijing, CN
Mansoureh Rezaei · Quincy, US
Michael D. Sintchak · Winchester, US
Francois Soucy · Stoneham, US
Stephen G. Stroud · Medford, US
Tricia J. Vos · Medford, US
Tzu-Tshin Wong · Belmont, US
He Xu · Needham, US
Tianlin Xu · Shrewsbury, US
Yingchun Ye · Belmont, US

Key dates

Filing date	Nov 9, 2016
Grant date	Sep 5, 2017
Priority date	—
Expiry date	Nov 9, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a compound of formula I:and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.