Cell processing cartridge for miniature cytometer
US9753026B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 30, 2013 |
| Grant date | Sep 5, 2017 |
| Priority date | — |
| Expiry date | Aug 10, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present embodiment relates to a miniaturized single-use apparatus for the preparation and analysis of suspensions of cells for flow cytometry. The cartridge apparatus is a unique combination, in order of function, of a miniature single-drive, two-cylinder syringe pump, a dual-channel stopcock valve that also performs volumetric measuring functions, a capillary-based fluid loading and measuring method, a miniaturized multistage interfacial-surface-generator mixer, a microfluidic magnetic cell selector, branching microfluidic channels with widths determined according to function, enclosed absorption-based disposal of potentially biohazardous liquids and a design compatible with manufacturing as a single-use device. In one embodiment the device for processing and labeling samples processes and samples small volumes, such as a drop of blood. The device can exist in hand-held versions, hand-carried versions and bench-scale versions of optical reading devices for flow cytometry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.