Surfactant-stripped micelle compositions with high cargo to surfactant ratio

US9757334B2 · kind B2 · utility

Assignee

• The Research Foundation for The State University of New York · US

Inventors

• Jonathan Lovell · Toronto, CA
• Yumiao Zhang · Buffalo, US
• Wentao Song · Beijing, CN
• Jumin Geng · Williamsville, US
• Chulhong KIM · Pohang-si, KR
• Mansik JEON · Daegu, KR

Key dates

• Filing date: Jul 2, 2015
• Grant date: Sep 12, 2017
• Expiry date: Jul 2, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K51/1227
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are compositions and methods relating to hydrophobic agent loaded-micelle. The micelles comprise surfactant (such as poloxamer) and have hydrophobic agents incorporated therein. The compositions substantially lack surfactant that is not associated with the micelles. The compositions are able to achieve high hydrophobic agent: surfactant molar ratio. The compositions can be used for drug delivery and imaging applications.