Labeled iodinated tropane formulation
US9757483B2 · kind B2 · utility
0Cited by
19References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2014 |
| Grant date | Sep 12, 2017 |
| Priority date | — |
| Expiry date | Oct 17, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21H5/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A diagnostic formulation is provided comprising a tropane having a radioactive concentration of at least 1.6 mCi/mL at least about 51 hours post creation. The diagnostic formulation optionally comprises a radiolabeled dopamine transporter (DAT) ligand useful in the diagnosis of Parkinson's disease (PS). One example of a radiolabeled dopamine transporter (DAT) ligand example is [123I]-2β-carbomethoxy-3β-(4-flurophenyl)-N-(3-iodo-E-allyl) nortropane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.