Protein chromatography matrices with hydrophilic copolymer coatings
US9758542B2 · kind B2 · utility
0Cited by
5References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 1, 2012 |
| Grant date | Sep 12, 2017 |
| Priority date | — |
| Expiry date | Nov 13, 2032 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/3828
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A coating of a random copolymer of acrylamide and a second monomer, e.g. glycidoxylmethacrylate, for a silica surface is described. The coating is applied to chromatographic support structures having silica based surfaces. The coating is functionalized to produce protein chromatography matrices that are particularly useful for extracting trace amounts of biomarker molecules from biological samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.