Patent · US Active

Compositions and methods for growth factor modulation

US9758576B2 · kind B2 · utility

10Cited by

121References

10Claims

0Family size

Assignee

Scholar Rock, Inc. · US

Inventors

Thomas Schurpf · Cambridge, US
Nagesh K. Mahanthappa · Cambridge, US
Michelle Straub · Watertown, US

Key dates

Filing date	Jul 9, 2015
Grant date	Sep 12, 2017
Priority date	—
Expiry date	Jul 9, 2035

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/71
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are antibodies that bind growth factor prodomain complexes, for example, growth factor prodomain complexes that include GDF-8 growth factor and GDF-8 prodomain. Also included are antibodies that bind growth factor prodomain complexes that have been altered by proteolytic processing.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.