Methods of reducing motion artifacts for optical coherence tomography angiography

US9759544B2 · kind B2 · utility

Assignees

• Carl Zeiss Meditec AG · DE
• University of Washington through its Center for Commercialization · US

Inventors

• Lin An · Portland, US
• Ruikang K. Wang · Seattle, US
• Utkarsh Sharma · Dublin, US

Key dates

• Filing date: Aug 7, 2015
• Grant date: Sep 12, 2017
• Expiry date: Aug 7, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01B9/02091
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for reducing motion artifacts in optical coherence tomography (OCT) angiography images is disclosed. The method is applied to the intensity or complex OCT data prior to applying the motion contrast analysis and involves determining sub-pixel level shifts between at least two B-scans repeated approximately at the same location and applying the sub-pixel level shifts to the B-scans to be able to correct for motion and accurately determine motion contrast signal. A preferred embodiment includes the use of 2D cross correlations to register a series of B-scans in both the axial (z-) and lateral (x-) dimensions and a convolution approach to achieve sub-pixel level frame registration.