Oral film containing opiate enteric-release beads
US9763879B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 11, 2013 |
| Grant date | Sep 19, 2017 |
| Priority date | — |
| Expiry date | Apr 11, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1652
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub-therapeutic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.