Therapeutic target for the treatment of cancers and related therapies and methods
US9763905B2 · kind B2 · utility
1Cited by
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7Claims
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Key dates
| Filing date | Mar 17, 2014 |
| Grant date | Sep 19, 2017 |
| Priority date | — |
| Expiry date | Mar 17, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/343
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of G-coupled protein receptor 40 (GPR40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by cancers, such as melanoma, medullary thyroid carcinoma, malignant peripheral nerve sheath tumors and neuroblastoma, and to reduce the incidence of metastases in such affected subjects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.