Methods of using Salmonella enterica presenting C. jejuni N-glycan or derivatives thereof

US9764021B2 · kind B2 · utility

Assignee

• Eidgenössische Technische Hochschule Zürich · CH

Inventors

• Karin Ilg · Zürich, CH
• Markus Aebi · Wettingen, CH
• Umesh Ahuja · Los Angeles, US
• Saba Amber · Los Angeles, US
• Flavio Schwartz · Zürich, CH

Key dates

• Filing date: Apr 8, 2016
• Grant date: Sep 19, 2017
• Expiry date: Apr 8, 2036

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to Salmonella enterica comprising at least pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N-glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface and, in particular, to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.