Synthesis of duocarmycin analogues
US9765077B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 29, 2015 |
| Grant date | Sep 19, 2017 |
| Priority date | — |
| Expiry date | May 29, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel Fmoc protected duocarmycin subunit and utilization as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.