Patent · US Active

Methods for preparation of fucose-linked site specific conjugates of proteins with toxins, adjuvants, detection labels and pharmacokinetic half life extenders

US9765158B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignee

ProBioGen AG · DE

Inventors

Hans Henning Von Horsten · Berlin, DE
Volker Sandig · Berlin, DE
Ingo Jordan · Berlin, DE
Karsten Winkler · Berlin, DE

Key dates

Filing date	May 31, 2012
Grant date	Sep 19, 2017
Priority date	—
Expiry date	May 28, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/41
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to eukaryotic cells for producing molecules having an atypical fucose analog on their glycomoieties and/or amino acids. It also relates to methods for producing molecules having an atypical fucose analog on their glycomoieties and/or amino acids and to molecules obtainable by said methods. It further relates to methods for producing conjugates comprising molecules having an atypical fucose analog on their glycomoieties and/or amino acids and pharmaceutical active compounds and to conjugates obtainable by said methods. In addition, the present invention relates to specific conjugates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.