Patent · US Active

Functionalized polymer hybrids

US9765169B2 · kind B2 · utility

0Cited by
39References
23Claims
0Family size

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Key dates

Filing dateApr 17, 2014
Grant dateSep 19, 2017
Priority date
Expiry dateSep 11, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H21/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method of synthesizing a polynucleotide composition includes attaching a compound including at least one initiator or at least one transfer agent for a reversible deactivation radical polymerization to an end of a nucleotide chain assembly immobilized upon a solid phase support during a solid phase synthesis of a polynucleotide so that the initiator or the transfer agent is attacked to the end of a nucleotide chain assembly in a manner which is stable under conditions of deprotection of the polynucleotide, and growing a polymer from the initiator of from a site of the chain transfer agent via the reversible deactivation radical polymerization to form the polynucleotide composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.