Bioreactor and rack for mounting bioreactors

US9765292B2 · kind B2 · utility

Assignees

• UNIVERSITY HOSPITAL OF BASEL · CH
• CELLEC BIOTEK AG · CH

Inventors

• Elia Piccinini · Toronto, CA
• David W. Wendt · Madison, US
• Adam Papadimitropoulos · Basel, CH
• Laura Spinelli · Lainate, IT
• Stefania Adele Riboldi · Milano, IT
• Francesco Greco · Cantù, IT
• Peter Iwatschenko · Geiselhöring, DE

Key dates

• Filing date: Jun 4, 2013
• Grant date: Sep 19, 2017
• Expiry date: Jun 4, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/14
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A bioreactor for preferably three-dimensional cell culturing comprises a scaffold chamber, a first tube, a second tube and a first valve with a scaffold adapter, a tube adapter and a medium adapter. The first valve has a housing with a longitudinal female portion ending in an opening and a longitudinal actuator being arranged through the opening of the female portion of the housing such that the actuator is arranged partially inside the housing and partially outside the housing, wherein the actuator of the first valve is axially moveable relative to the housing of the first valve between a first position in which the first valve is in the operation position and a second position in which the first valve is in the medium change position. By providing the actuators in the first valve which is applied by axial movements, operation of the bioreactor can be comparably simple and safe.