Method for aerobically producing alanine or a compound produced using alanine

US9765370B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Hans-Georg Hennemann · Marl, DE
• Steffen Schaffer · Herten, DE
• Mirja Wessel · Bochum, DE
• Markus Pötter · Shanghai, CN
• Jan Christoph Pfeffer · Hanau, DE
• Thomas Haas · Munster, DE
• Jasmin Corthals · Bochum, DE
• Eva-Maria ECKL · Marl, DE
• Silvana Roeder · Freiburg im Breisgau, DE
• Wolfgang Kroutil · Graz, AT
• Arne Skerra · Freising, DE

Key dates

• Filing date: Mar 25, 2013
• Grant date: Sep 19, 2017
• Expiry date: Jun 4, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/005
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process for producing alanine, including culturing a cell under aerobic conditions in an aqueous phase in the presence of an inorganic nitrogen source, and then contacting the aqueous phase and the cell cultured in the aqueous phase with a hydrophobic organic phase. The cell is a prokaryotic or a lower eukaryotic cell and expresses a recombinant alanine dehydrogenase.