Affinity methods and compositions employing electronic control of pH

US9766207B2 · kind B2 · utility

Assignees

• Bio-Rad Laboratories, Inc. · US
• Technion Research & Development Foundation Limited · IL

Inventors

• Aran Paulus · Heitersheim, DE
• Camille Diges · Concord, US
• Roumen Bogoev · San Marcos, US
• Inbal Zafir-Lavie · Misgav Am, IL
• Sricharan Bandhakavi · Albany, US
• Annett Hahn-Windgassen · Sunnyvale, US
• Anton Posch · Grafing, DE
• Elad Brod · Rekhasim, IL
• Uri Sivan · Haifa, IL

Key dates

• Filing date: Aug 26, 2014
• Grant date: Sep 19, 2017
• Expiry date: Jan 3, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5302
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods and devices for purifying, detecting, and collecting analytes fractionated based on pI, separating analytes via electrophoresis and pI, and purifying a target molecule using pI focusing and subsequent crystallization are provided.