Methods of optimizing chromatographic separation of polypeptides
US9766217B2 · kind B2 · utility
20Cited by
1References
9Claims
0Family size
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Key dates
| Filing date | Sep 8, 2007 |
| Grant date | Sep 19, 2017 |
| Priority date | — |
| Expiry date | Feb 21, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2218/12
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described are methods for determination of peptide specific parameter(s) of a mixture comprising a target peptide and a related impurity (or impurities) to be used in a simulation model of chromatographic separation using mathematical model(s). Also described are chromatographic simulation methods using above determined parameters, as well as computer systems and computer programs for performing one or more of the above method(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.