Patent · US Active

Human-derived insect-resistant gene and anti-CRY1B toxin idiotype single-chain antibody encoded thereby and application thereof

US9770038B2 · kind B2 · utility

4Cited by

0References

2Claims

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Assignee

JIANGSU ACADEMY OF AGRICULTURAL SCIENCES INSTITUTE OF FOOD SAFETY AND MONITORING TECHNOLOGY · CN

Inventors

Xianjin Liu · Xinzhai, CN
Chongxin Xu · 安丰镇, CN
Xiao Zhang · Shanghai, CN
Yuan Liu · Suzhou, CN
Yajing Xie · 安丰镇, CN
Cunzheng Zhang · 安丰镇, CN
Xiangyang Yu · 安丰镇, CN
Donglan Wang · Xinzhai, CN

Key dates

Filing date	Jan 9, 2015
Grant date	Sep 26, 2017
Priority date	—
Expiry date	Jan 9, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/622
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided are a human-derived insect-resistant gene having a nucleotide sequence represented by SEQ ID NO.1, and an anti-Cry1B toxin idiotype single-chain antibody encoded by said human-derived insect-resistant gene and having an amino acid sequence represented by SEQ ID NO.2. The idiotype single-chain antibody is a β-type and has insecticidal activity, and after expression by the prokaryotic system, the primary culture thereof has binding activity to Cnaphalocrocis medinalis midgut peritrophic membrane specific receptor BBMV.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.