Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
US9770349B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 24, 2007 |
| Grant date | Sep 26, 2017 |
| Priority date | — |
| Expiry date | Sep 16, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0058
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.