Methods of using gas-filled microvesicles covalently bound to an antigen
US9770411B2 · kind B2 · utility
1Cited by
10References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2011 |
| Grant date | Sep 26, 2017 |
| Priority date | — |
| Expiry date | May 8, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.