2-aminothiazole derivatives and methods of preparing and using the same

US9771340B2 · kind B2 · utility

Assignee

• WUHAN INNAMUNE PHARMACEUTICAL CO., LTD. · CN

Inventors

• FENGCHAO JIANG · 红钢城街道, CN
• Ping Zhou · Plainsboro, US
• Jianguo CHEN · 安丰镇, CN
• Yue Wang · Beijing, CN
• Baoshuai Cao · 红钢城街道, CN
• Jia Yan · 红钢城街道, CN

Key dates

• Filing date: Sep 1, 2013
• Grant date: Sep 26, 2017
• Expiry date: Sep 1, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

2-aminothiazole derivatives represented by formula (I), where R1 and R2 represent cycloalkyls, respectively; or R1 represents a substituted aromatic group, and R2 represents H, a C1-C11 alkyl, —CH2Ph (benzyl), or a methyl ether including a C1-C11 alkyl. R3 is a substituent including an amino group. X represents a carbonyl or a methylene and n is an integer from 0 to 5.