Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors
US9771366B2 · kind B2 · utility
6Cited by
4References
20Claims
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Key dates
| Filing date | Feb 17, 2017 |
| Grant date | Sep 26, 2017 |
| Priority date | — |
| Expiry date | Feb 17, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions comprising the derivatives, and methods of using the derivatives in treating diseases or conditions associated with RSK activity:wherein R2, R4a, R4b, R11, R12, and n are defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.