Influenza virus
US9771564B2 · kind B2 · utility
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10Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 20, 2010 |
| Grant date | Sep 26, 2017 |
| Priority date | — |
| Expiry date | Jul 20, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16161
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel influenza virus wherein both the NS and the PB1 gene segments are modified and wherein the PB1-F2 open reading frame is modified by introduction of at least one stop codon. Specifically, the influenza virus is lacking functional NS1 and PB1-F2 proteins. Additionally, a vaccine formulation comprising the modified influenza virus is provided and its use for prevention of influenza vaccination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.