Rodent comprising mouse artificial chromosome vector
US9775331B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Dec 18, 2014 |
| Grant date | Oct 3, 2017 |
| Priority date | — |
| Expiry date | Dec 18, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a mouse artificial chromosome vector, comprising: a natural centromere derived from a mouse chromosome; a mouse-chromosome-derived long-arm fragment formed by deleting a long-arm distal region at a mouse chromosome long-arm site proximal to the centromere; and a telomere sequence, wherein the vector is stably retained in a cell and/or tissue of a mammal. In addition, disclosed are cells or non-human animals comprising the vector, and use of the cells or non-human animals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.