Patent · US Active

PRMT5 inhibitors and uses thereof

US9777008B2 · kind B2 · utility

15Cited by
55References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 8, 2016
Grant dateOct 3, 2017
Priority date
Expiry dateJun 8, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.