Anti-virulance compositions and methods
US9782363B2 · kind B2 · utility
1Cited by
0References
7Claims
0Family size
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Key dates
| Filing date | Oct 14, 2013 |
| Grant date | Oct 10, 2017 |
| Priority date | — |
| Expiry date | Oct 14, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) or an ortholog of AgrA includes administering to the bacterium an amount of a pharmaceutical composition effective to inhibit the synthesis of one or more virulence factors by the bacterium, the pharmaceutical composition including an AgrA antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.