Amidine substituted β-lactam compounds, their preparation and use as antibacterial agents

US9782390B2 · kind B2 · utility

Assignee

• AiCuris GmbH & Co. KG · DE

Inventors

• Burkhard Klenke · Wuppertal, DE
• Irith Wiegand · Wuppertal, DE
• Guido Schiffer · Wuppertal, DE
• Heike Broetz-Oesterhelt · Wuppertal, DE
• Samarendra N. Maiti · Swan Hills, CA
• Jehangir Khan · Edmonton, CA
• Andhe Reddy · Swan Hills, CA
• Zhixiang Yang · Edmonton, CA
• Mostafa Hena · Edmonton, CA
• Guofeng Jia · Edmonton, CA
• Ou Ligong · Edmonton, CA
• Hong Liang · Edmonton, CA
• Judy Yip · Swan Hills, CA
• Chuanjun Gao · Edmonton, CA
• Sabiha Tajammul · Edmonton, CA
• Rahim Mohammad · Edmonton, CA
• Ganguli Biswajeet · Edmonton, CA

Key dates

• Filing date: Dec 19, 2016
• Grant date: Oct 10, 2017
• Expiry date: Dec 19, 2036

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel β-lactam compounds, their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.