Preparing tooth-like structure using stem cell

US9782443B2 · kind B2 · utility

Assignee

• Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences · CN

Inventors

• Duanqing Pei · Tangxia, CN
• Jinglei Cai · 流花街道, CN
• Pengfei Liu · 安丰镇, CN
• Shubin Chen · Shrewsbury, US
• Yanmei Zhang · Tangxia, CN

Key dates

• Filing date: Feb 5, 2013
• Grant date: Oct 10, 2017
• Expiry date: Feb 5, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2506/45
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The usage of a stem cell in preparation of a tooth-like structure is provided. And a culture medium, a method for preparing an epithelial-like cell, a kit for preparing an ameloblast, a method for preparing an ameloblast are also provided. Specifically, the culture medium comprises a basal medium, which is DMEM/F12 medium; N2 supplement; retinoic acid; and BMP-4.