Fraction I-IV-1 precipitation of immunoglobins from plasma
US9782477B2 · kind B2 · utility
1Cited by
15References
61Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 25, 2013 |
| Grant date | Oct 10, 2017 |
| Priority date | — |
| Expiry date | Nov 9, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/145
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Among other aspects, the present invention provides methods for the manufacture of blood protein compositions from pooled plasma. In one embodiment, the invention provides an alcohol fractionation scheme that allows for significant increases in the yield of blood proteins purified from the starting plasma sample. In a specific embodiment, a method for fractionating pooled plasma is provided, the method comprising an initial low pH, high alcohol precipitation step. The present invention also provides pharmaceutical compositions of therapeutic blood proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.