Patent · US Active

Glucagon superfamily peptides exhibiting nuclear hormone receptor activity

US9783592B2 · kind B2 · utility

2Cited by

12References

21Claims

0Family size

Assignee

INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION · US

Inventors

Richard D. DiMarchi · Carmel, US
Bin Yang · Waltham, US
Brian Finan · Bloomington, US

Key dates

Filing date	Jul 24, 2015
Grant date	Oct 10, 2017
Priority date	—
Expiry date	Jul 24, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/72
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are glucagon superfamily peptides conjugated with NHR ligands that are capable of acting at a nuclear hormone receptor. Also provided herein are pharmaceutical compositions and kits of the conjugates of the invention. Further provided herein are methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the conjugates of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.