Antibodies, variable domains and chains tailored for human use
US9783593B2 · kind B2 · utility
17Cited by
43References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 2013 |
| Grant date | Oct 10, 2017 |
| Priority date | — |
| Expiry date | May 2, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/8509
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to the provision of antibody therapeutics and prophylactics that are tailored specifically for human use. The present invention provides libraries, vertebrates and cells, such as transgenic mice or rats or transgenic mouse or rat cells. Furthermore, the invention relates to methods of using the vertebrates to isolate antibodies or nucleotide sequences encoding antibodies. Antibodies, heavy chains, polypeptides, nucleotide sequences, pharmaceutical compositions and uses are also provided by the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.