Microfluidic manifold for shear sensitive fluids

US9784396B2 · kind B2 · utility

Assignee

• The Charles Stark Draper Laboratory, Inc. · US

Inventors

• Joseph L. Charest · Cambridge, US
• Jeffrey T. Borenstein · Holliston, US
• Alla Epshteyn · Brookline, US
• Daniel I. Harjes · Acton, US
• Christopher DiBiasio · Cambridge, US
• Vijaya Kolachalama · Brookline, US

Key dates

• Filing date: Feb 17, 2015
• Grant date: Oct 10, 2017
• Expiry date: Apr 15, 2035

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B29C2045/0077
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A microfluidic device is provided. A manifold having a first channel, a second channel, and a third channel configured to transport blood can be coupled to a substrate defining an artificial vasculature. The first channel can be configured to carry blood in a first direction. Each of the second and third channels can couple to the first channel at a first junction and can be configured to receive blood from the first channel. The second channel can be configured to carry blood in a second direction away from the first direction. The third channel can be configured to carry blood in a third direction away from the second direction. The first, second, and third channels can be non-coplanar.