Methods for protecting eyes against neurodegeneration caused by glaucoma in age-related hereditary glaucoma using radiation
US9789336B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 21, 2009 |
| Grant date | Oct 17, 2017 |
| Priority date | — |
| Expiry date | Jan 21, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N5/1084
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for treating, preventing and/or reducing neurodegeneration in subjects with neurodegenerative disease, such as those neurodegenerative diseases that affect the eye, including glaucoma, using radiation, such as gamma radiation or X-ray radiation, either alone or together with a bone marrow transfer treatment. The method includes irradiating a targeted area of an animal, such as the eye region, with radiation, either alone or followed by injection with T-cell depleted bone marrow cells. Also a method for screening and/or selecting agents and/or treatment methods for inhibiting, treating and/or reducing neurodegeneration, particularly the neurodegeneration of the eye that occurs as a consequence of glaucoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.