Patent · US Active

KDM1A inhibitors for the treatment of disease

US9790195B2 · kind B2 · utility

9Cited by
0References
58Claims
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Assignee

Inventors

Key dates

Filing dateAug 6, 2014
Grant dateOct 17, 2017
Priority date
Expiry dateAug 6, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDMIA, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.