Method of diagnosing and treating asphyxia

US9791459B2 · kind B2 · utility

Assignee

• InfanDx AG · DE

Inventors

• Matthias Keller · Maineville, US
• Hans-Peter Deigner · Lampertheim, DE
• David Enot · Creully, FR
• Matthias Kohl · Rottweil, DE
• Ronnaug Solberg · Oslo, NO
• Ola Didrik Saugstad · Oslo, NO
• Therese Koal · Innsbruck, AT

Key dates

• Filing date: May 4, 2010
• Grant date: Oct 17, 2017
• Expiry date: May 4, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A90/10
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.