Dry powder inhalers with dual piercing members and methods of operating same

US9795749B2 · kind B2 · utility

Assignee

• Oriel Therapeutics, Inc. · US

Inventors

• Gerald A. Thoe · Chippewa Falls, US
• James G. Skakoon · Windom, US
• David A. Schuelke · Hudson, US
• Thomas W. Ruckdeschel · Cary, US
• David Harris · Hollis, US
• Scott Alexander Lewis · Rancho Cordova, US
• Andrew Murray Gow · Cambridge, GB
• Jonathan David Tuckwell · Cambridge, GB

Key dates

• Filing date: Feb 12, 2015
• Grant date: Oct 24, 2017
• Expiry date: Jan 29, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2202/064
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.