Devices, systems, and methods for detecting nucleic acids using sedimentation
US9795961B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2012 |
| Grant date | Oct 24, 2017 |
| Priority date | — |
| Expiry date | Sep 14, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/045
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Embodiments of the present invention are directed toward devices, systems, and method for conducting nucleic acid purification and quantification using sedimentation. In one example, a method includes generating complexes which bind to a plurality of beads in a fluid sample, individual ones of the complexes comprising a nucleic acid molecule such as DNA or RNA and a labeling agent. The plurality of beads including the complexes may be transported through a density media, wherein the density media has a density lower than a density of the beads and higher than a density of the fluid sample, and wherein the transporting occurs, at least in part, by sedimentation. Signal may be detected from the labeling agents of the complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.