Patent · US Active

5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative

US9796709B2 · kind B2 · utility

1Cited by
2References
33Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 2014
Grant dateOct 24, 2017
Priority date
Expiry dateDec 12, 2034

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P13/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof has an excellent LCAT-activating effect and is useful as an active ingredient in a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disturbance, and restenosis caused by angiogenesis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia, or renal disease, particularly, an anti-arteriosclerotic agent, wherein R is an optionally substituted aryl group or an optionally substituted heteroaryl group, and R1 is a hydrogen atom or a hydroxy group.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.