Production of tissue engineered heart valves
US9801713B2 · kind B2 · utility
1Cited by
19References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 4, 2016 |
| Grant date | Oct 31, 2017 |
| Priority date | — |
| Expiry date | Jan 4, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention is directed to methods for preparing artificial heart valves by preconditioning a matrix seeded with endothelial cells and smooth muscle cells differentiated from isolated progenitor cells. These cell seeded matrices are exposed to fluid conditions that mimic blood flow through the heart to produce tissue engineered heart valves that are analogous to native heart valves.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.