Preservative-free ophthalmic pharmaceutical formulation
US9801813B2 · kind B2 · utility
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2References
18Claims
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Key dates
| Filing date | Oct 13, 2014 |
| Grant date | Oct 31, 2017 |
| Priority date | — |
| Expiry date | Oct 13, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for manufacturing an ophthalmic formulation of a carbonic anhydrase inhibitor, hydroxyl ethyl cellulose (HEC), and a beta-adrenergic antagonist for use in the treatment of ocular hypertension and glaucoma wherein the ophthalmic pharmaceutical formulation is devoid of benzalkonium chloride or any other preservatives. The present process for manufacturing is simpler, cost effective process to prepare the pharmaceutical ophthalmic formulation in a single tank, without the use of additional tanks that can be sterile filtered.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.